It is reported that the bioactive ingredients in A. auricula and examined its hepatoprotective effect on acute alcohol induced liver injury in mice. auricula have protective effects on acute alcoholic liver injury through different metabolic pathways. 8 reported that the polysaccharides from A. auricula have significant protective effects on acute alcoholic injury.
7 Recently, there are many studies showing that the polysaccharides, melanin and protein in A. auricula), also named “heimuer” in Chinese, is an important edible fungus with high carbohydrate and protein contents and has been recognized as a healthy food. 6 Therefore, the exploration of natural substances from food materials with antioxidant activity to alcohol is needed for preventing and treating damage caused by the oxidative stress of alcohol.Īuricularia auricula ( A. When the level of alcohol in a person's blood is high, alcohol metabolism produces excessive reactive oxygen species (ROS), which can induce oxidative stress and lead to acute alcoholic injury. 3 As we all know, excessive drinking of alcohol usually induces a variety of organ disorders, 4,5 including neurological, liver, gastrointestinal and cardiovascular diseases, and even cancer. 2 Alcohol abuse and related diseases have become a global public health problem, and the incidence rate is also increasing in recent years. It is reported by the World Health Organization that there are 237 million men and 46 million women affected by harmful drinking. 1 Many people drink hard liquor chronically or acutely due to their addiction to alcohol. Introduction Alcohol is a psychoactive drug with dependence-producing potential and has been widely used in beverages as a recreational substance worldwide for centuries. auricula fermentation broth had protective effects on the liver and stomach of mice with acute alcoholism, and could be used as a potential functional food to prevent liver and stomach damage caused by acute alcoholism. auricula fermentation broth had protective effects on the liver and stomach of mice with acute alcoholism, and significantly reduced the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), total cholesterol (TC) and triglycerides (TG) in serum. auricula could significantly enhance the activity of NRK cells and protect NRK cells from H 2O 2 damage. Cell experiments showed that the fermentation broth of A. auricula fermentation broth had a strong ability to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) and hydroxyl radicals. Antioxidant activity test results showed that the A. auricula fermentation by structural analysis. Furthermore, the characteristic structures of active substances such as proteins, polysaccharides and phenolics were found in the A. auricula were monitored, and the results showed the content of polysaccharides and protein in the two kinds of fermentation broth after the fermentation was completed. The changes of physical and chemical indexes during the fermentation of A.
auricula fermentation broth was prepared by adding Bacillus subtilis, lactic acid bacteria, and Saccharomyces cerevisiae to A. auricula) fermentation broth on the liver and stomach of mice with acute alcoholism was studied.
In this paper, the protective effect of Auricularia auricula ( A.
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